HUMAN SYNTHETIC PEPTIDE VACCINE FOR CONTRACEPTION TARGETING SPERM
نویسندگان
چکیده
منابع مشابه
Human sperm-specific peptide vaccine that causes long-term reversible contraception.
A novel dodecamer peptide sequence, YLP(12), was identified on human sperm that is involved in oocyte binding. We investigated its immunocontraceptive effects in a murine model. A vaccine was prepared by conjugating the synthetic YLP(12) peptide with the binding subunit of recombinant cholera toxin. Vaccination of female mice by i.m. or intranasal routes without any additional adjuvant induced ...
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ژورنال
عنوان ژورنال: Archives of Andrology
سال: 2004
ISSN: 0148-5016
DOI: 10.1080/aan.50.2.113.119